Ying Yang
Tongji Medical College,China
Title: Risk Factors of Chronic Obstructive Pulmonary Disease in Chinese Mainland: A Systematic Review and Meta-Analysis
Biography
Biography: Ying Yang
Abstract
In recent years, some epidemiological surveys of risk factors for COPD have been done in China, but the relevance is shown different in these surveys. A systematic review and meta-analysis was undertaken to identify the main risk factors of COPD in Chinese mainland population.
Methods:
All language, original, full-text research articles published between January 1 1989 and September 31, 2016 were searched through electronic databases, including The Cochrane Library, PubMed, CNKI, CBM, WanFang Data and so on. Case-control studies on the incidence of COPD were systematically included and analyzed using Comprehensive Meta-Analysis v2 software.
Results:
Twenty studies involving 7372 cases and 8394 controls were included in this study. Ten factors were extracted as risk factors of COPD, including smoking (OR=2.29, 95%CI: 1.94 to 2.71), occupational exposure (OR=2.07, 95%CI: 1.30 to 3.27), family history of respiratory system disease (OR=1.96, 95%CI: 1.61 to 2.38), coal or biomass burning (OR=2.19, 95%CI: 1.56 to 3.08), low BMI (OR=3.28, 95%CI: 2.74 to 3.92), gender (male) (OR=1.42, 95%CI: 1.06 to 1.88), low education degree (OR=1.29, 95%CI: 1.03 to 1.61), passive smoking (OR=1.76, 95%CI: 1.23 to 2.53), allergy history (OR=2.19, 95%CI: 1.16 to 4.13) and chronic occupational exposure respiratory disease during childhood (OR=2.47, 95%CI: 1.43 to 4.27).